Yuuki Family's House is where most of the main characters in To LOVE-Ru series live.
- Rito Yuuki, the main protagonist.
- Mikan Yuuki, Rito's little sister.
- Saibai Yuuki, Rito's father. Rarely visit home due to his work as a mangaka and work deadline.
- Ringo Yuuki, Rito's mother and Saibai's wife. Like her husband, she rarely visits home due to her work as a fashion designer.
- Lala Satalin Deviluke, the eldest princess of planet Deviluke. She currently live in a parallel dimension inside Yuuki's house with her sisters, Momo and Nana.
- Nana Astar Deviluke, the older twin princess, Lala's little sister.
- Momo Belia Deviluke, the younger twin princess, Lala's litte sister.
- Celine, a child-like humanoid/plant alien. Originally she was a gift from Lala on Rito's 16th birthday, and a rare multi-story sentient sunflower.
- Nemesis (formerly), used to live inside Rito's body.